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The Dual Wire Myograph is for simultaneous testing of two arteries with diameters of 60µm - 3mm. This is performed in a 10ml. acid-resistant stainless steel chamber with ports in the chamber cover for rapid draining and gas supply. The chamber can be divided for separate testing of each vessel. A window underneath allows morphological or fluorescence measurements. Myographs can be arranged conveniently side by side for multiple testing.

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The Automated Wire Myograph is for simultaneous testing of two arteries with diameter of 60µm - 3mm. This is performed in a acid-resistant stainless steel chamber, with ports in the chamber cover for rapid draining, filling and gas supply. The chamber can be divided for separate testing of each vessel. A window underneath allows morphological or fluorescence measurements. Myographs can be arranged conveniently side by side for multiple testing.

Brochure / Spare parts & Accessories / user manual

The Multi Myograph is intended for studies of four isolated vessel (dia. 60µm – 10mm.) preparations simultaneously, mounted as ring preparations. The sensitive force transducers allow measurements of isometric muscle tension while micropositioners allow the attraumatic setting of vessel diameter. Each unit has individually controlled gas inflow and suction conduits and chambers are round stainless steel that simplifies cleaning. The system is automatically heated to a given set temperature.

Brochure / Spare parts & Accessories / user manual

The confocal wire myograph is designed for providing highly resolved images of fluorescent dyes within living tissues using a laser-scanning microscope. Combining LSCM with myography allows simultaneous measurements of isometric force and e.g. intracellular [Ca2+] or pH to be obtained in living isolated blood vessels.

The bath design allows easy access for the type of high numerical aperture lenses used in standard upright confocal microscopy. The top part may be tipped further, which not only facilitates easier maintenance, but also eases the mounting procedure.

Also, by using reverse mounting supports designed specifically to allow vertical positioning, an isolated blood vessel can be positioned directly above the chamber window permitting use of lenses with working distances as low as 0.25mm in an inverted LSCM, which is advantageous for simultaneous electrophysiological measurements.

A heating system gives electronic feedback for maintaining chamber temperature above ambient temperature. The chamber cover includes ports for rapid draining and filling, and for gas supply.

Using the myograph on a confocal microscope, data acquisition is possible on force and temperature. It is done either by using the analogue outputs or the serial interface.

Brochure / Spare parts & Accessories / user manual